Serra Mesa vacation rentals
We found 43 vacation rentals — enter your dates for availability
Discover a selection of 24 homes and other vacation rentals in Serra Mesa that are perfect for your trip. Vacation rentals offer the amenities you expect for you and your friends, family, or even pets, such as parking and a washer and dryer. What you'll find is a rental to meet everyone's needs, including options that are accessible or non-smoking.
Find spaces that suit your style
House
Condo/Apartment
Find the best place to stay - Serra Mesa
Amazing Urban Oasis - Close to Everything!
Sleeps 6 · 2 bedrooms · 1+ bathroom
Top rated rentals - Serra Mesa
Photo gallery for Spacious San Diego Family home centrally located to stadium & famous beaches!
Spacious & Comfortable
- Peace of mindOur Book with Confidence guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
- More for lessMore space, more privacy, more amenities — more value